Monday, March 20, 2006

Fears of contaminated bone and skin grafts are being felt by unsuspecting patients following the revelation that funeral homes may have been looting corpses.

Janet Evans of Marion Ohio was told by her surgeon, “The bone grafts you got might have been contaminated”. She reacted with shock, “I was flabbergasted because I didn’t even know what he was talking about. I didn’t know I got a bone graft until I got this call. I just thought they put in screws and rods.”

The body of Alistair Cooke, the former host of “Masterpiece Theatre,” was supposedly looted along with more than 1,000 others, according to two law enforcement officials close to the case. The tissue taken was typically skin, bone and tendon, which was then sold for use in procedures such as dental implants and hip replacements. According to authorities, millions of dollars were made by selling the body parts to companies for use in operations done at hospitals and clinics in the United States and Canada.

A New Jersey company, Biomedical Tissue Services, has reportedly been taking body parts from funeral homes across Brooklyn, New York. According to ABC News, they set up rooms like a “surgical suite.” After they took the bones, they replaced them with PVC pipe. This was purportedly done by stealth, without approval of the deceased person or the next of kin. 1,077 bodies were involved, say prosecuters.

Investagators say a former dentist, Michael Mastromarino, is behind the operation. Biomedical was considered one of the “hottest procurement companies in the country,” raking in close to $5 million. Eventually, people became worried: “Can the donors be trusted?” A tissue processing company called LifeCell answered no, and issued a recall on all their tissue.

Cooke’s daughter, Susan Cooke Kittredge, said, “To know his bones were sold was one thing, but to see him standing truncated before me is another entirely.” Now thousands of people around the country are receiving letters warning that they should be tested for infectious diseases like HIV or hepatitis. On February 23, the Brooklyn District Attorney indicted Mastromarino and three others. They are charged with 122 felony counts, including forgery and bodysnatching.

Saturday, June 27, 2009

The death of Michael Jackson on Thursday has caused retail demand for his songs and for memorabilia to increase.

Yesterday, the top nine selling items at Apple’s iTunes Store were albums by Jackson, with first and second being a “hits” album and the 1982 album Thriller.

Amazon.com similarly reported selling more Jackson merchandise in the 24 hours following his death than it had sold in the preceding 11 years, and that sales of Jackson CDs accounted for 60% of its total business on Thursday. Yesterday morning the top seller in the album chart for Amazon’s U.K. division was Off the Wall, followed by Bad and Thriller in second and third places, respectively.

Many stores, including Graywhale CD Exchange in Salt Lake City, several record stores in Danville, Virginia, and many retailers in New Zealand, have all reported selling out of Jackson’s CDs and DVDs. The flagship store of Tower Records Japan, in Shinjuku, sold out of several of Jackson’s DVDs and ran low on several other items including CDs. The Danville Register Bee recommended to its readers that if they had record players they should investigate antique and charity shops, after one antique shop reported discovering three Jackson Five vinyl albums in its basement.

The effect of the increase in sales had an effect on stock prices. Midday yesterday, Apple shares rose around 2%, Amazon shares rose around 1.3%, and eBay shares rose by 0.64%. Stock market analysts predict that this will be a short-term effect, however. Scott Fullman, an investment strategist at WJB Capital Group in New York, stated “This is going to be one of these events that will have an immediate impact and then wane out in a week or two.”.

In Las Vegas, 21 items of Jackson memorabilia, including handwritten lyrics for Jackson’s song “Bad” and the shirt that Jackson wore on his Victory Tour in 1984, sold at auction yesterday at the Planet Hollywood Resort and Casino for a total of USD$205,000, with the shirt, at USD$52,500 the most expensive individual item.

eBay has reported an increase in individuals auctioning Jackson memorabilia. These range from records to a Fedora hat signed by Jackson.

Also for sale on eBay and elsewhere are tickets to the This Is It concerts, at the O2 arena, where Jackson had been scheduled to perform. Ticket sellers such as Ticketmaster, Seatwave, and AEG Live have announced that they will be refunding concert tickets. But under standard contract law such refunds only apply to the original purchasor of the ticket, who dealt with the ticket companies directly. Anyone buying a ticket on eBay only has recourse against the seller on eBay that they bought from, and even then only if it was explicitly stated in the terms and conditions of the particular eBay sale that a refund was available.

At the 2009 Glastonbury Festival, stalls have been selling commemorative T-shirts to Festival attendees, with various different slogans including “Michael Jackson R.I.P 1958–2009” and “I was at Glasto 09 when Jacko died”. T-shirt vendors also appeared outside of the UCLA Medical Center where paramedics took Jackson, proferring for USD$10 T-shirts with the slogan “in loving memory of Michael Jackson” and a silhouette of Jackson, although they had few takers.

In Union Square in New York, one street artist was selling hand-made buttons that have pictures of Jackson’s album covers on them. In Times Square, another T-shirt vendor was selling T-shirts printed with copies of the front page of USA Today that reported Jackson’s death.

One observer, Allison Southwick (a Better Business Bureau spokeswoman), commented “I’m honestly expecting to see a Web site pop up by the end of the day selling Michael Jackson commemorative plates.” Whilst such commemorative plates have yet to appear, collectors have been offering commemorative stamps of Jackson for sale on eBay and elsewhere. Several commemorative stamps of Jackson already exist. Saint Vincent and the Grenadines issued $5, $2, $1, and 60¢ Michael Jackson stamps in 1985, as part of its Leaders Of The World series. Tanzania issued a 350s stamp, part of a Famous Black Entertainers set, in 1990. Guinea issued a 500f stamp in 1991. St Vincent issued another $2 Jackson stamp in 1991, as part of Famous Entertainers series. And Grenada issued a 60¢ Jackson stamp, part of its Gold Record Winners series in 1992.

Gore Vidal once remarked of the death of rival Truman Capote that it was a “good career move”. The death of an artist does serve to increase the popularity of their works. People have speculated whether this will be a temporary or a permanent thing for Jackson.

Jim Lentz, who is the Chief Operating Officer of American Royal Arts (a memorabilia dealership in Boca Raton), asked “Is he Elvis or Marilyn Monroe, or is he Mike Tyson?”.

Elvis Presley died at 42, officially of heart failure. Stores sold out of his records and souveniers within hours of the news of his death. In the 20 years following his death, RCA Records sold approximately 400 million of his recordings.

In the days and weeks immediately following Presley’s death, RCA had to sub-contract pressing to other companies, as it was unable by itself to keep up with demand. Sony Corporation announced yesterday that it had received “unprecedented” levels of orders for CDs of Jackson’s music, and was considering boosting production. It had received 150,000 orders for CDs at its music unit in Tokyo. “The amount is unprecedented for one day and we think we need to consider increasing the production of CDs that we plan to sell from July.” said a spokesman for the company. Amazon has been informing customers buying Jackson CDs that they might have to wait between 1 and 3 weeks for their orders to be shipped.

Tuesday, January 15, 2008

Satire site Uncyclopedia, a parody of online encyclopedia Wikipedia, has been labeled by the Malaysian government as dangerous. The Internal Security Department of Malaysia issued the warning today, saying that the site has “messages and information insulting Malaysia”.

The warning notes the creation date of the website as being 5 January 2005, and hosted by Wikia, Inc., both of which are correct. However, it claims Wikia owns Wikipedia; Wikipedia is a charitable non-profit website owned by the non-profit Wikimedia Foundation, while Wikia is an independent, for-profit company.

The report evidently mentions that Uncyclopedia covers Malaysian “history, culture, the political leaders, the government, the national song and the name / history of the national flag,” none of which is “correct”. They accuse the website of helping to reinforce a bad international image of their country.

There are no reports of the site being blocked from access within the country, only this statement, which urges Malaysians not to circulate the content.

Uncyclopedia’s article on Malaysia begins:

The site has fired back with a parody article posted at the site under their UnNews section, titled Uncyclopedia Internal Security Department warns on Malaysia. The article suggests that the “Internal Security Department of the Uncyclomedia Foundation,” which is a facetious and fictitious parent organization of Uncyclopedia, identifies Malaysia “as a dangerous country… It warned its people not to use the country today.”

There are forty-seven individual language editions of Uncyclopedia, including Tolololpedia, which is written in Bahasa Melayu, the Malay language. This is in addition to fictional “language” editions which include Oscar Wilde, Newspeak, N00b, White Supremacist, and Re: PharmaccgRy.

Tuesday, July 12, 2011

A recently-published international study shows that in long-term couples, men are more satisfied with their relationships, and women are more satisfied with their sex lives.

The study, which also says that men enjoy cuddling (i.e. hugging and kissing) more than women, was published in the Archives of Sexual Behaviour by the Kinsey Institute in Indiana University Bloomington. More formally known as the Kinsey Institute for Research in Sex, Gender and Reproduction, the organization is also known for reporting in the 1940s that young adults were having sex. The report observed more than 1,000 couples from the US, Japan, Germany, Spain, and Brazil. All of the survey participants were aged 40 to 70, and all of the couples had been together for at least a year. The average duration of the relationship was 25 years.

Japanese men were more likely to be satisfied with their sex lives than American men, and Japanese and Brazilian women were more likely to be satisfied with their sex lives than American women, though the study did not control for other factors such as age.

Women in relationships lasting at least 15 years were more likely to be happy with their sex lives than women in relationships lasting less than 15 years. According to the report’s author Julia Heiman, “It’s possible that women became more satisfied over time because their expectations change, or life changes when their children grow up.”

Men who reported regular hugging and kissing in their relationships were three times as happy as those without cuddling.

Jennifer Bass, communications director at the Kinsey Institute, says that “this study makes it clear our assumptions aren’t always borne out by research,” referring to common beliefs that men prefer sex while women prefer cuddling.

Tuesday, June 15, 2010

Scientology is facing renewed criticism, due to an extensive exposé in the Florida newspaper the St. Petersburg Times which contains revealing accounts of women involved in the organization who say they were forced to have abortions. Multiple different female members of the Scientology group called the Sea Org said they were pressured to have abortions, and were threatened with separation from their families, hard labor, interrogations, and shunning, if they did not comply.

Women that came forward to the St. Petersburg Times said that those who did not wish to undergo an abortion were shunned by others within the Sea Org group, and were labeled as “out ethics” and “degraded beings”. The Sea Org consists of 6,000 members of Scientology, who sign billion-year contracts to work for the organization for multiple lifetimes. Joining the Sea Org is considered a high calling within Scientology.

L. Ron Hubbard, the founder of Scientology, stated his appreciation for families within the Sea Org. Scientology’s subsequent leader, David Miscavige, issued an order that children were to be banned in the Sea Org. The mandate by Miscavige asserted that children hampered the productivity of the Scientology order.

Scientology representative, Tommy Davis denied all of the assertions made by the women. “There is no church policy to convince anyone to have an abortion, and the church has never engaged in such activity. The decision to have a child or terminate a pregnancy is a personal decision made by a couple. That applies to all Scientologists. If any current or former Sea Org member ever ‘pressured’ someone to have an abortion, they did so independently, and that action was not approved, endorsed or advocated by the church,” stated Davis to the St. Petersburg Times.

Another woman is suing the Scientology organization in United States federal court, and stated she was threatened with severe repercussions if she did not have an abortion. Claire Headley, 35, a member of the Sea Org when she was in Scientology, told the St. Petersburg Times, “The policy was if a staff member became pregnant, that they were to have an abortion.”

In 1991, Headley became a member of the Sea Org at age sixteen, and began work with the division of the organization in Los Angeles, California. She married at age seventeen, while a member of the organization. Headley said that officials within Scientology leadership pressured her to have two abortions: one at age nineteen, and another at age 21. Headley believed she had “no choice”, as she had witnessed other women that refused to have abortions instructed to perform manual labor, with one pregnant woman ordered to dig ditches. Headley said that during pressure to have her second abortion she was forbidden to phone her husband to discuss the decision. She spent a total of thirteen years in the Sea Org.

Laura Dieckman, 31, said that she was enthusiastic about beginning a family when she became pregnant within Scientology at age seventeen, but was instructed to have an abortion. In a federal lawsuit against Scientology, Dieckman stated she joined with the Sea Org at the age of twelve, and at age sixteen she married another member of the group, Jesse DeCrescenzo. She said she was pressured to have an abortion in 1996.

Dieckman said to the St. Petersburg Times: “I was pounded for two days by the top person in my organization … about how the baby wasn’t a baby yet, it was just tissue and it wouldn’t matter if I aborted the baby.” Dieckman left Scientology in 2004. In a video posted to the website of the St. Petersburg Times, Dieckman emotionally recounted how she had immediately regretted going through with the procedure, “They will do an ultrasound before the procedure so you see the heartbeat. … I’m lying there … and I was like, ‘No.’ But it’s too late. I’d already done it.”

Natalie Hagemo said that 20 years ago at age nineteen, she was pressured by Scientology officials to have an abortion, but she resisted. Hagemo gave birth to Shelby on August 20, 1990. Hagemo’s daughter was recruited into the Sea Org at age 14. Shelby contacted her mother a week later wanting to leave the Sea Org; Hagemo had a difficult time getting Shelby out of the group. It was not until this year that Hagemo told her daughter about experiencing pressure from Scientology officials to have an abortion.

The St. Petersburg Times received sworn depositions from additional women including Sunny Pereira, who said they were intimidated into having abortions they did not wish to undergo. “They put you in this position where you’re weighing the lives of all these people you’re supposed to be saving against this one little tiny speck of nuisance that’s growing inside of you,” said Pereira. Spokesman Tommy Davis stated the women were accusing Scientology of forced abortions because of choices they now “appear to regret”.

In Nevada, Republican party candidate for the United States Senate, Sharron Angle, was the focus of criticism for her support of a Scientology-associated program. Angle’s opponent, incumbent Senator and Senate Majority Leader Democrat Harry Reid, took out a 30-second negative political ad critical of Angle for supporting “a Scientology plan to give massages to prisoners”. The prison program Angle had supported was based on techniques developed by Scientology founder, L. Ron Hubbard. Angle had previously been the subject of a similar ad in the Republican primary, generated by the campaign of her opponent Sue Lowden. Sharron Angle is pro-life, and The New York Times columnist Ramesh Ponnuru noted her position against abortion helped her win the Republican primary. “Angle would not have been able to unite populist conservatives and beat the party establishment’s candidate had she been pro-choice,” noted Ponnuru.

Thursday, April 27, 2006

18 members of the Granny Peace Brigade (an anti-war activist group) were acquitted on charges of disorderly conduct during a protest outside a Times Square military recruiting center in New York City last fall.

The defendants in the case – some were in their 80s and 90s – were charged with two counts of disorderly conduct during their October 17, 2005 protest of the Iraq war.

The Judge Neil Ross says that his verdict is not a critique of any particular police agency but that evidence showed there was no blockage of pedestrian traffic and anyone who wanted to enter the recruiting center could do so. The Manhattan courtroom erupted into applause after Judge Ross said that the prosecution “failed to prove each defendant guilty of each charge.”

The defense lawyer Norman Siegel said that the women were pleased by the verdict and was quoted saying that, “They are great Americans, and they walk the shoes of great Americans who have made America the place that it is,”

If any of the defendants were convicted, they each could have faced up to 15 days in prison.

Friday, January 26, 2007

Ângelo A. Chora et. al. are reporting in the Journal of Clinical Investigation this week that carbon monoxide (CO) and the heme oxygenase-1 protein protect against the symptoms of multiple sclerosis (MS) in the related mouse model of experimental autoimmune encephalomyelitis (EAE).

Multiple sclerosis is a chronic, inflammatory disease that affects the central nervous system (CNS). Although many patients are largely unaffected by their disease, MS can cause impaired mobility and disability in more severe cases.

The research group from the Gulbenkian Institute in Portugal used the EAE mouse model of MS to study the effects of the Heme oxygenase-1 (HO-1) protein encoded by the HMOX1 gene.

HO-1 knockout mice, lacking both copies of the gene (not producing the protein), showed a more severe progression of the disease compared to wild-type mice, having normal levels of the protein. The symptoms of the disease were reversed when the HO-1 protein expression was induced using cobalt protoporphyrin IX.

During MS attacks the body’s own immune system destroys the myelin sheath surrounding nerve cells in the brain and spinal cord. Pathogenic T helper cells are triggered by Antigen-presenting cell (APCs) within the brain stem. The disease can cycle between attacks (relapses) followed by remission, suggesting that there is an underlying regulatory system. The HO-1 protein had been identified previously as a possible candidate for a protective gene.

HO-1 degrades excess heme within the body acting as the rate controlling step when under inflammatory conditions. The HO-1 heme degradation pathway produces as products equal amounts of free heme, carbon monoxide and biliverdin.

Carbon monoxide was also shown to limit the effects of the disease. Mice were exposed to a high concentration of CO for 20 days within a chamber. Mice exposed to CO had limp tails, but were more mobile than the mice in the control experiment which displayed hind limb paralysis.

It is still unknown exactly how carbon monoxide slows down the symptoms of EAE, possibly through the mopping up of free radicals, or through promoting the binding of iron to heme (decreasing radical production).

The experiments found that HO-1 did not affect the development or function of regulatory T cells. For a beneficial effect HO-1 needed to be expressed in dendritic cells, causing inhibition of MHC-II proteins, involved in presenting antigens, and inflammatory cytokines (IFN-?).

These experiments open up new possibilities for MS therapies, involving the expression of HO-1 in suppressing the development of MS.

The article went online on the 25th January 2007 and will be printed in the Journal of Clinical Investigation in February.